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LL37 (5mg)

LL37 (5mg)

Original price was: $64.99.Current price is: $49.99.

Download Certificate of Analysis

1 published certificate

SKU: YPB.244 Category:

Description

A single-component research material supplied for controlled research environments. LL-37 is a synthetic cathelicidin-derived peptide used in research exploring innate immunity, antimicrobial pathways, and wound-healing models in controlled systems.

Composition

• LL-37
• Appearance: Lyophilized powder in a sealed research vial

Research Focus (non-clinical)

• Characterization of LL-37 in antimicrobial activity assays
• Studies on immune modulation and inflammatory pathway signaling
• Evaluation in cell culture and tissue models related to epithelial repair
• Stability and solubility profiling under laboratory storage conditions

For qualified research professionals and institutional laboratories. Not for human use.

Documentation & Quality Assurance

Each lot is sourced through our verified global supply chain with emphasis on traceability and quality control.These documents are reviewed internally and displayed as they become available. Independent third-party testing is also performed on select lots to confirm identity, purity, and alignment with our internal specifications.

Important Notice

This product is intended for laboratory research use only. It is not intended for human or veterinary use, and must not be used for diagnostic, therapeutic, or clinical purposes.
This material is not a drug, medical device, or dietary supplement, and has not been evaluated by the U.S. Food and Drug Administration.

Quality & Manufacturing

We work directly with the manufacturers. Each supplier is reviewed for reliability, documentation integrity, and transparency in testing.

We require a verified purity of 99% or higher and perform independent third-party spot testing to confirm that select lots meet our internal standards for identity, purity, and composition. Where available, endotoxin testing results are included on Certificates of Analysis to verify laboratory purity; their inclusion is for research quality assessment only and does not imply suitability for human or veterinary use.

All research materials are sealed for integrity and packaged for stability during storage and transport from manufacturing through final delivery.

Additional information

Weight 0.0625 lbs
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Published Scientific Research

Explore the full library of peer-reviewed studies, clinical data, mechanism breakdowns, and molecular specifications for LL37 (5mg).

All research is sourced from PubMed-indexed journals for informational and educational purposes only. For Research Use Only (RUO). Not for human use.

View Full Research Library →

Storage Instructions

All products from House of Compounds are manufactured using a lyophilization (freeze-drying) process. This method is designed to maintain product integrity and allows vials to remain stable during shipping for approximately 3–4 months.

Once a vial is reconstituted with bacteriostatic water, it should be stored in the refrigerator to help maintain stability. Under these conditions, reconstituted material is generally considered stable for up to 30 days.

Lyophilization is a dehydration technique in which compounds are frozen and then exposed to low pressure. This causes the water in the vial to sublimate directly from solid to gas, leaving behind a stable, crystalline white structure. This powder can be kept at room temperature until reconstitution.

Upon receipt, products should be stored away from heat and light. For short-term use, refrigeration at approximately 4°C (39°F) is suitable. For long-term storage (several months to years), vials may be placed in a freezer at approximately -80°C (-112°F). Freezing is the preferred method for preserving product stability over extended periods.

⚠️ Important Notice:
These products are intended for research use only. Not for human consumption.

Related products

Research Use Only

The following peer-reviewed publications reference compounds for laboratory and in vitro research purposes only. Not for human or animal use. Not intended to diagnose, treat, cure, or prevent any disease or condition.

PubMed — Peer-Reviewed Research

Published Scientific Research

Peer-reviewed laboratory studies investigating research peptides

Molecular Analysis PubMed

A sonosensitive diphenylalanine-based broad-spectrum antimicrobial peptide.

Nature biomedical engineering 2025

The antimicrobial effect of antimicrobial peptides is typically slow; they can be rapidly biodegraded and often have non-selective toxicity and elaborate sequences. Here we report a short peptide that is activated by ultrasound, that shows high broad-spectrum antibacterial efficiency (>99%) against clinically isolated methicillin-resistant bacteria (specifically, Staphylococcus aureus, Escherichia coli, Staphylococcus epidermidis, Enterobacter cancerogenus and Pseudomonas aeruginosa) with 15 m

View Full Study
In Vitro Study PubMed

Milk-derived extracellular vesicles functionalized with anti-tumour necrosis factor-α nanobody and anti-microbial peptide alleviate ulcerative colitis in mice.

Journal of extracellular vesicles 2024

In mice with chronic UC, simultaneously introducing VHH and an antimicrobial peptide LL37 into EV (EV), then administering orally improved intestinal barrier, inflammation and microbiota balance, resulted in relief of UC-induced depression and anxiety. Collectively, we demonstrated that oral delivery of EV effectively alleviated UC in mice and TAT efficiently loaded biologics into EV to confer protection from degradation in the gastrointestinal tract.

View Full Study
Mechanism Study PubMed

Opposing Roles of Antimicrobial Peptides in Skin Cancers.

Current pharmaceutical design 2022

In this review, we describe the roles and mechanisms of AMPs in skin cancer development.

View Full Study
Molecular Analysis PubMed

Screening Peptides that Activate MRGPRX2 using Engineered HEK Cells.

Journal of visualized experiments : JoVE 2021

Identifying ligands specific to therapeutically significant cell receptors is crucial for many applications, including the design and development of new therapeutics. Mas related G-protein receptor-X2 (MRGPRX2) is an important receptor that regulates mast cell activation and, thus, directs the general immune response.

View Full Study
In Vitro Study PubMed

Antiviral Activities of Human Host Defense Peptides.

Current medicinal chemistry 2020

Peptides with broad-spectrum antimicrobial activity are found widely expressed throughout nature. As they participate in a number of different aspects of innate immunity in mammals, they have been termed Host Defense Peptides (HDPs). Due to their common structural features, including an amphipathic structure and cationic charge, they have been widely shown to interact with and disrupt microbial membranes. Thus, it is not surprising that human HDPs have activity against enveloped viruses as well

View Full Study
In Vitro Study PubMed

Efficacy of Antigonococcal CMP-Nonulosonate Therapeutics Require Cathelicidins.

The Journal of infectious diseases 2020

Here, we identify a key mechanism of action for the efficacy of CMP-NulOs.

View Full Study

Important Research Notice: These products are research chemicals intended exclusively for in vitro laboratory research by qualified professionals. Not for human or animal consumption. Not approved by the FDA for any therapeutic purpose. Sold strictly for scientific research applications only.

View Full Research Library — Peer-Reviewed Studies, Clinical Data & Molecular Specs →

Frequently Asked Questions

Essential information about our research-grade peptides and quality standards.

Peptides are short chains of amino acids linked by peptide bonds, typically consisting of 2-50 amino acids. They serve as the building blocks of proteins and play crucial roles in biological processes.

Research peptides are synthesized versions of naturally occurring peptides, manufactured to precise specifications for use in scientific studies.

Key characteristics: High purity (≥98%), lyophilized form for stability, accompanied by Certificates of Analysis (COA), and manufactured under strict quality control protocols.

Peptide purity refers to the percentage of the target peptide present in a sample, measured via High-Performance Liquid Chromatography (HPLC).

Our Standard: All our research peptides maintain ≥98% purity, verified by third-party laboratory testing and documented in our Certificates of Analysis.

Higher purity is critical for research because impurities can interfere with experimental results and compromise the reproducibility of studies.

All products are supplied in lyophilized powder form within sterile, sealed vials. This format provides:

  • Maximum stability: Extended shelf life compared to liquid solutions
  • Precise measurement: Researchers can work with desired quantities
  • Contamination protection: Sealed vials prevent environmental exposure
  • Shipping durability: Powder form is more stable during transit

Lyophilized peptides:

  • Store at -4°F for long-term storage (up to 24 months)
  • Store at 36-46°F (refrigerated) for short-term storage (up to 3 months)
  • Keep away from light, moisture, and repeated temperature fluctuations

We supply research-grade peptides to:

  • Academic and university research laboratories
  • Pharmaceutical and biotechnology companies
  • Independent research institutions
  • Licensed professionals conducting legitimate scientific research

We maintain rigorous quality control through a multi-step verification process:

  • HPLC Analysis: Every batch tested to verify ≥98% purity
  • Mass Spectrometry: Molecular weight confirmation for peptide identity
  • Third-Party Testing: Independent laboratory verification
  • Sterility Protocols: Aseptic handling and packaging procedures
  • Batch Documentation: Complete traceability from synthesis to delivery

"Research Use Only" (RUO) is a classification indicating that a product is intended exclusively for laboratory research and experimental investigation.

All orders are shipped with research-grade handling protocols:

  • Packaging: Insulated containers with cold packs when required
  • Carriers: USPS Priority Mail
  • Processing: Orders placed before 12 PM EST ship same business day
  • Tracking: Full tracking information provided via email

At House of Compounds, product quality, consistency, and research integrity are at the core of everything we do. Due to the specialized nature of our products and their designation as research-use-only compounds, we maintain a strict return and refund policy to ensure product safety and quality standards remain uncompromised.

All Sales Are Final

We do not accept returns or offer refunds for:

  • Ordering the wrong product
  • Change of mind
  • Improper storage, handling, or misuse after delivery
  • Failure to review product details before purchase

Once an order has been shipped and delivered, it is considered final.

Damaged, Defective, or Incorrect Orders

If your order arrives damaged, defective, or you receive the wrong item, please contact us within 48 hours of confirmed delivery.

Email: support@houseofcompounds.com

Please include:

  • Your order number
  • A detailed explanation of the issue
  • Clear photos of the product and packaging

Our team will review your claim and determine whether a replacement or refund is appropriate.

Eligible Replacement or Refund Scenarios

Refunds or replacements may be approved only under the following circumstances:

  • You received an incorrect item
  • Your order arrived damaged during transit
  • Your product arrived defective
  • Your package was not delivered due to an error on our end

When approved, we will first attempt to provide a replacement product. If a replacement is unavailable, a refund may be issued at our discretion.

Non-Eligible Situations

We do not offer refunds or replacements for:

  • Opened or used products
  • Unauthorized returns
  • Incorrect shipping information provided by the customer
  • Delays caused by shipping carriers after the package has been dispatched
  • Products damaged due to improper handling after delivery

Contact Us

If you have questions regarding your order, please reach out to our support team:
support@houseofcompounds.com

We're committed to providing high-quality research compounds and making sure every order is handled with care.

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⚠️ Research Use Only — Legal Acknowledgment

All products on this website are sold strictly for in vitro research and laboratory use only.

  • Not for human or veterinary use, consumption, or application
  • Not FDA-approved to diagnose, treat, cure, or prevent any disease
  • Buyer assumes full responsibility for legal compliance in their jurisdiction
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This information is collected for merchant compliance and regulatory purposes.

Please select your research affiliation to continue.

By clicking "Accept," you confirm:

  • You are at least 21 years of age
  • You are a qualified researcher or laboratory professional
  • You represent the affiliation type selected above
  • You understand these products are for research purposes only

Your selection is stored locally and may be recorded for compliance purposes.